What is the distribution function for a population with a disease?

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Homework Help Overview

The discussion revolves around a mathematical model for a population affected by a disease, focusing on the death density function and its implications for cumulative distribution functions. The problem involves determining constants in the function and expressing the cumulative death distribution in a specified form.

Discussion Character

  • Mathematical reasoning, Assumption checking

Approaches and Questions Raised

  • Participants explore the integration of the death density function to find the constant c in terms of k, questioning the divergence of their results. There is also a discussion about the appropriate limits for integration, with suggestions to integrate from 0 to infinity instead of negative infinity.

Discussion Status

Some participants have provided guidance on the integration process and the interpretation of the results, while others are still verifying their findings. There is an ongoing exploration of the implications of the constants and the structure of the cumulative distribution function.

Contextual Notes

Participants note that the model assumes no deaths occur before the onset of the disease, which influences the limits of integration and the formulation of the cumulative distribution function.

altegron
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Homework Statement



Consider a population of individuals with a disease. Suppose that [tex]t[/tex] is the number of years since the onset of the disease. The death density function, [tex]f(t) = cte^{-kt}[/tex], approximates the fraction of the sick individuals who die in the time interval [t, t+Δt] as follows:
Fraction who die: [tex]f(t)\Delta t = cte^{-kt} \Delta t[/tex]
where [tex]c[/tex] and [tex]k[/tex] are positive constants whose values depend on the particular disease.

(a) Find the value of c in terms of k.

(b) Express the cumulative death distribution function in the form below. Your answer will be in terms of k.

[tex] C(t)=\left\{\begin{array}{cc}A(t),& t < 0\\<br /> B(t), & t \geq 0\end{array}\right[/tex]

Homework Equations



[tex]P(t) = \int_{-\inf}^t p(x) dx[/tex]

The Attempt at a Solution



To solve part a, I know that [tex]\lim_{t\rightarrow\infty} P(t) = 1[/tex]. So c and k must have values so that it equals one. So I integrate [tex]f(t)[/tex] with the relevant equations to get:

[tex] \frac{-(kt+1) \cdot e^{-kt} \cdot c}{k^2}[/tex]

from negative infinity to t.

The problem is that this diverges to negative infinity and doesn't give me a meaningful answer. So what do I do?


Also, how do I get the the bar with a superscript and subscript for 'from a to b' in tex?
 
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Hi altegron! :smile:
altegron said:
Consider a population of individuals with a disease. Suppose that [tex]t[/tex] is the number of years since the onset of the disease.

[tex]P(t) = \int_{-\infty}^t p(x) dx[/tex]

No, nobody died before the onset of the disease! :wink:

(and that bar would be [tex]|_a^b\ \big|_a^b\ \Big|_a^b\ \bigg|_a^b\ \Bigg|_a^b[/tex])
 
tiny-tim said:
Hi altegron! :smile:


No, nobody died before the onset of the disease! :wink:

(and that bar would be [tex]|_a^b\ \big|_a^b\ \Big|_a^b\ \bigg|_a^b\ \Bigg|_a^b[/tex])

Thanks for the response,

That makes sense -- I guess that means I should integrate from 0 to infinity then?

[tex] \lim_{x\rightarrow\infty} \int_0^x cte^{-kt} dt = 1[/tex]

Which is easier written as

[tex] \int_0^{\infty} cte^{-kt} dt = 1[/tex]

Which is:

[tex] \frac{-(kt+1) \cdot e^{-kt} \cdot c}{k^2} \bigg|_0^{\infty} = 1 [/tex]

The infinity term goes to zero and the zero term (negated for subtraction) is:

[tex] \frac{(k \cdot (0)+1) \cdot e^{-k \cdot (0)} \cdot c}{k^2} = 1 [/tex]

[tex] \frac{(0+1) \cdot e^{0} \cdot c}{k^2} = 1 [/tex]

[tex] \frac{c}{k^2} = 1 [/tex]

So, finally:

[tex] c = k^2[/tex]

That seems plausible but I don't know how to check it.

Then for part b, I know [tex]A(t) = 0[/tex] because the disease hasn't started yet.

For [tex]B(t)[/tex] we use the integral we've already computed, from zero to t years. We know the value at zero is 1 (actually, -1, but it is being subtracted), so we have:

[tex] B(t) = 1 - \frac{(kt+1) \cdot e^{-kt} \cdot c}{k^2}[/tex]

And that looks correct on my calculator when I graph it with k=1.
 
Looks good! :biggrin:

(btw, that | is really only used for "value at", with only a subscript …

for integrals, use [] … LaTeX will automatically size them to fit if you type "\left[" and "\right]" :wink:)
 

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