- #1
TytoAlba95
- 132
- 19
I'm stuck in a dev bio paper. The relevant extract is porovided below:
Human germ cell development begins with the specification of PGCs, which is expected to happen at the onset of gastrulation (developmental week 2) in the posterior epiblast of early postimplantation embryos. During gestation (weeks 3–5), the definitive PGCs migrate from the yolk sac wall through the hindgut to the developing gonads, where they then undergo sex-specific differentiation after week 9. Whereas the male germ cells enter mitotic quiescence synchronously and undergo meiosis after puberty, female human germ cells enter meiosis asynchronously over an extended time period.
The source: cell.
Human germ cell development begins with the specification of PGCs, which is expected to happen at the onset of gastrulation (developmental week 2) in the posterior epiblast of early postimplantation embryos. During gestation (weeks 3–5), the definitive PGCs migrate from the yolk sac wall through the hindgut to the developing gonads, where they then undergo sex-specific differentiation after week 9. Whereas the male germ cells enter mitotic quiescence synchronously and undergo meiosis after puberty, female human germ cells enter meiosis asynchronously over an extended time period.
The source: cell.