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etotheipi

1. Flammable Maths (Maths)

2. BlackPenRedPen (Maths)

3. 3Blue1Brown (Maths)

4. Andrew Dotson (Physics)

5. Zach Star (Engineering)

There's also Nottingham University's 60 symbols and periodic videos, in addition to some old warhorses numberphile and computerphile.

Wondered whether anyone would recommend some other notable channels, not necessarily restricted to youtube, though!