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When neurotransmitters are released into the synaptic gap, do they bind with receptors only once and then disengage once, or do they bind and disengage repeatedly?
Thanks.
Thanks.
Moonbear said:Others stay at the membrane where they can continue interacting until endocytosed by the cell releasing them. This would also depend on whether the action was postsynaptic or presynaptic as to how much recycling could occur.
neurocomp2003 said:its once isn't it...cuz of the all or none firing principle...that once teh NT are received by the receptors of the post synapse that they enter the knob for decomposition?
Math Is Hard said:When you say that some stay at the membrane where they can continue interacting, does that mean they release and re-bind with other receptors, or the same receptor, or maybe both?
Math Is Hard said:I guess I imagine some of these little NTs bouncing from receptor to receptor, propigating a new action potential with each binding, but I am not sure if it can work that way.
quasi426 said:I'm a little bit confused here. Isn't endocytosed and internalized the same thing. How can the cell release something during endocytosis.
Math Is Hard said:I thought the fate of the NT was always reuptake by the presynaptic neuron or destruction by the MAO process.
DocToxyn said:The best example of a neurotransmitter which is predominantly terminated by metabolism would be acetylcholine and its degradation by acetylcholinesterase.
quetzalcoatl9, that was an interesting example. Is this also how "nerve gas" works?.. although DA in the cleft is first hit by catechol-o-methyltransferanse (COMT)
Math Is Hard said:quetzalcoatl9, that was an interesting example. Is this also how "nerve gas" works?
Math Is Hard said:hey Doc, this is probably a dumb question but what is the "DA" you referred to here:
Neurotransmitters are chemical messengers that allow communication between neurons in the brain and nervous system.
Neurotransmitters are released into the synaptic gap through a process called exocytosis, where they are transported from the axon terminal of one neuron to the dendrites of another.
Neurotransmitters play a crucial role in regulating various functions in the brain, including emotions, cognition, and movement.
Yes, imbalances in neurotransmitter levels have been linked to various mental health disorders, such as depression, anxiety, and schizophrenia.
Neurotransmitters can influence behavior by activating or inhibiting specific pathways in the brain, which can impact mood, thoughts, and actions.