Zoonotic disease: Buruli ulcer

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In summary, a terrifying disease known as Buruli ulcer is stalking seaside areas in Australia. It is caused by a species of flesh-eating bacteria called Mycobacterium ulcerans and its mode of transmission is not known. While it is part of the same family of bacteria that causes tuberculosis and leprosy, it is an environmental bacterium and produces a unique toxin called mycolactone. This disease has been reported in 33 countries but the reasons for its decline and recent increase are still unclear. It is not limited to tropical regions and can also be contracted in subtropical and temperate areas. There is currently no known prevention or vaccine for this disease. Some believe that it may be harbored in possums in Australia.
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NY Times - A Terrifying Disease Stalks Seaside Australia: Flesh-Eating Ulcers
https://news.yahoo.com/terrifying-disease-stalks-seaside-australia-120741684.html
What looked like a sunburn on the top of a man's foot turned out to be an infection of a species of flesh-eating bacteria! The species is Mycobacterium ulcerans.

According to WHO, "the mode of transmission is not known and there is no prevention for the disease." "The organism belongs to the family of bacteria that causes tuberculosis and leprosy, which provides an opportunity for collaboration with these disease programmes. However, M. ulcerans is an environmental bacterium and produces unique toxin – mycolactone."

https://www.cdc.gov/buruli-ulcer/index.html
https://www.who.int/news-room/fact-sheets/detail/buruli-ulcer-(mycobacterium-ulcerans-infection)

Buruli ulcer has been reported in 33 countries in Africa, the Americas, Asia and the Western Pacific. Most cases occur in tropical and subtropical regions except in Australia, China and Japan. Out of the 33 countries, 14 regularly report data to WHO.

The annual number of suspected Buruli ulcer cases reported globally was around 5000 cases up until 2010 when it started to decrease until 2016, reaching its minimum with 1961 cases reported. Since then, the number of cases has started to rise again every year, up to 2713 cases in 2018. The reasons for the decline and for the recent increase are not clear.
I thought it might be a case of warm (tropical) water. But apparently, there is a theory that it harbors in possums (in Victoria, Australia).

https://en.wikipedia.org/wiki/Buruli_ulcer
 
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This is terrifying! I have never heard of this disease before. It's worrying to think that it can be contracted even in subtropical and temperate regions. Does anyone know what the best way to protect oneself is? Is there a vaccine or something?
 

1. What is a zoonotic disease?

A zoonotic disease is a disease that can be transmitted from animals to humans.

2. What is Buruli ulcer?

Buruli ulcer is a chronic skin and soft tissue infection caused by the bacterium Mycobacterium ulcerans. It is most commonly found in tropical and subtropical regions.

3. How is Buruli ulcer transmitted?

Buruli ulcer is transmitted through contact with contaminated water, soil, or vegetation. The exact mode of transmission is still not fully understood.

4. What are the symptoms of Buruli ulcer?

The first symptom of Buruli ulcer is usually a painless swelling or nodule on the skin. This can progress to an ulcer with a characteristic undermined edge. Other symptoms may include fever, fatigue, and swelling of nearby lymph nodes.

5. How is Buruli ulcer treated?

Buruli ulcer can be treated with a combination of antibiotics, typically rifampicin and either streptomycin or clarithromycin. Surgery may also be necessary to remove dead tissue and promote healing. Early detection and treatment are crucial for a successful recovery.

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