Medical Vitamin D Crucial to Activating Immune Defenses

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Research indicates that vitamin D plays a crucial role in immune function, particularly in T cell activation. Professor Carsten Geisler highlights that T cells extend a vitamin D receptor to search for this nutrient; without sufficient vitamin D, T cells cannot mobilize effectively against pathogens. A clinical trial led by Dr. Mitsuyoshi Urashima revealed that children aged six to 15 who received vitamin D had a significantly lower incidence of flu compared to those given a placebo, suggesting vitamin D may be more effective than vaccines for flu prevention. Additionally, studies from the Intermountain Medical Center Heart Institute link vitamin D deficiency to an increased risk of coronary artery disease, with evidence suggesting that supplementation could mitigate this risk and improve overall cardiovascular health. These findings will be presented at the upcoming American College of Cardiology conference.
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Professor Carsten Geisler from the Department of International Health, Immunology and Microbiology explains that "when a T cell is exposed to a foreign pathogen, it extends a signaling device or 'antenna' known as a vitamin D receptor, with which it searches for vitamin D. This means that the T cell must have vitamin D or activation of the cell will cease. If the T cells cannot find enough vitamin D in the blood, they won't even begin to mobilize. "
 
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Biology news on Phys.org
http://www.timesonline.co.uk/tol/news/uk/scotland/article7061778.ece

Only one in ten children, aged six to 15 years, taking the sunshine vitamin in a clinical trial came down with flu compared with one in five given a dummy tablet. Mitsuyoshi Urashima, the Japanese doctor who led the trial, told The Times that vitamin D was more effective than vaccines in preventing flu.

Vitamin D was found to be even more effective when the comparison left out children who were already given extra vitamin D by their parents, outside the trial. Taking the sunshine vitamin was then shown to reduce the risk of flu to a third of what it would otherwise be.
 
http://www.physorg.com/news187879711.html"

Researchers at the Intermountain Medical Center Heart Institute last fall demonstrated the link between vitamin D deficiency and increased risk for coronary artery disease. These new studies show that treating vitamin D deficiency with supplements may help to prevent or reduce a person's risk for cardiovascular disease and a host of other chronic conditions. They also establish what level of vitamin D further enhances that risk reduction.

Study findings will be presented at the American College of Cardiology 59th annual scientific session in Atlanta.
 
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