Whether uracil was an amino acid or not

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Uracil is identified as a nitrogenous pyrimidine base found in RNA, not an amino acid. It pairs with adenine in double-stranded RNA and is substituted by thymine in DNA. While uracil contains nitrogen, it lacks an amino group (NH2), which is essential for classification as an amino acid. The discussion highlights the roles of uracil and thymine, noting that neither is superior overall; each has specific advantages in their respective contexts. Thymine contributes to the stability of DNA, which is crucial for genetic information storage, while uracil may facilitate the attraction of anticodons during protein synthesis. The exact reasons for the distinct roles of these bases remain a topic for further exploration.
jimmy p
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I while back (in the distant days when i was in education...I'm a day out of education now!) we were studying amino acids in chemistry, and I asked my chemistry teacher whether uracil was an amino acid or not. She didnt know but said she would find out, which she didnt, so I am asking the experts now!

"Is uracil an amino acid?" :approve:
 
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No uracil is a nitrogenous pyrimidine base found in RNA but not DNA. In double-stranded RNA it pairs with adenine. In DNA, uracil is replaced by thymine.
 
Uracil is a base found in RNA and is derived from pyrimidine, it contains nitrogen but no amino group (NH2) so it's not an amino acid.
 
YEH! I wanted to answer :-p
 
You snooze you lose :biggrin:
 
So it is a fake? what a clever thing protein synthesis is. That doesn't really make much sense though, what is the point in thymine? Why is uracil better?
 
jimmy p said:
So it is a fake? what a clever thing protein synthesis is. That doesn't really make much sense though, what is the point in thymine? Why is uracil better?

Uracil isn't 'superior' to Thymine on a whole, but each have their advantages in each situation.
Thymine is present in DNA - the encoded information for synthesis of proteins, while it is replaced by uracil in mRNA/tRNA/rRNA.
While I'm not sure of the reason for it i would expect thymine possibly holds the DNA together in a more stable manner (as it is storage) and uracil holds some advantage in attracting the anticodons carrying amino acids to the ribosomes. Perhaps uracil exhibits a greater electronegativity?
Who knows.., that's merely my uninformed ramblings, perhaps the mentors can clear this up.
 
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