Apparent death from supplement overdose: news analysis

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Discussion Overview

The discussion revolves around the implications of supplement consumption and its associated risks, particularly in relation to fatalities and health outcomes in the US. It includes analysis of labeling requirements, the categorization of supplements, and the potential dangers of specific substances.

Discussion Character

  • Debate/contested
  • Exploratory
  • Technical explanation

Main Points Raised

  • Some participants highlight that there are approximately 23,000 fatal and near-fatal events related to supplement consumption in the US each year, questioning the validity of conflating different types of supplements.
  • Others suggest a need to differentiate between harmful supplements and those that are beneficial, such as Vitamin B, and to analyze the impact of deficiencies versus supplement use.
  • A participant references a meta-analysis and discusses the low mortality rates associated with Vitamin D3, contrasting it with the higher death rates from Covid-19.
  • Concerns are raised about the potential side effects of specific supplements, such as white mulberry leaves, particularly in relation to interactions with other medications.
  • There is a mention of the challenges in conducting meaningful statistical analysis on supplement-related deaths due to the low incidence rates.

Areas of Agreement / Disagreement

Participants express differing views on the dangers of supplements, with some emphasizing the need for careful analysis and differentiation, while others appear skeptical about the claims made in opinion pieces regarding supplement risks. The discussion remains unresolved with multiple competing perspectives.

Contextual Notes

Limitations include the lack of clarity on definitions of "supplements," the potential for mislabeling, and the complexity of analyzing data on supplement-related deaths versus deaths from deficiencies.

jim mcnamara
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A non-technical opinion piece that claims there are many fatal and near-fatal events, ~23000 total, in the US every year -- with regard to supplement consumption/abuse. Additionally, it explains US labeling requirements and available remediation for problems related to supplement usage. Which is why it is here in Medical, and not in Discussion.
 
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Biology news on Phys.org
There ain't no law west of the Pecos, Jim.
 
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jim mcnamara said:
Summary: https://www.nbcnews.com/think/opini...ock-wife-points-supplements-dangers-rcna45009

A non-technical opinion piece that claims there are many fatal and near-fatal events, ~23000 total, in the US every year -- with regard to supplement consumption. Additionally, it explains US labelling requirements and available remediation for problems related to supplement usage. Which is why it is here in Medical, and not in Discussion.

Simple minded people will read such an article and conflate the dangers of shady weight loss supplements containing meth-like chemicals, with things like Vitamin B supplements. It would be interesting to filter out the deaths due to product mislabeling/contamination, as well as the deaths due to supplements which are unrelated to basic health, such as stimulants, weight loss supplements, body building supplements, sexual enhancement supplements, etc, and then analyze deaths prevented by using supplements, deaths stemming from deficiencies, and compare with deaths from taking supplements. The sheer number of deaths due to Covid-19+Vit.D would be nice to know.
 
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972416/ - meta-analysis
https://ods.od.nih.gov/factsheets/vitamind-healthprofessional/ poop sheet for practitioners
Rates of Vit D3 associated deaths in the US are very low, India uses Vit D2 and there are reported problems with it. D3 seems to be much less problematic there.

US mortality rates are really very low, so as an example, so let's say:
US death rate is 2/year associated with vit D3, and 150000/year for Covid-19. You cannot do meaningful statistical analysis on data like that, IMO.

Since Vit D3 problems are rare they make news. News reporting of this on a scale of quality
Code:
+1 -> +10:  
-5.
...off the scale. My opinion of course.

CDC expert panel on Vitamin D:
https://www.cdc.gov/nccdphp/dnpa/nutrition/pdf/vitamin_d_expert_panel_meeting.pdf ... bring coffee it's long and detailed
 
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Re:"My opinion of course." Always a valuable commodity!
But white mulberry leaves? Really? If my wife began ingesting some arcane vegetation...but as prospects narrow with age perhaps an element of panic sets in. (There's some evidence eating the leaves of morus alba may induce mild hallucinations, which may be a reasonable reaction to your husband becoming involved in politics.) We're all wandering around in the wilderness.
 
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White mulberry may also increase the side effects of cholesterol-lowering medications and should be used with caution in patients using benzodiazepines, barbiturates, or antidepressants
-- drugs.com
And there are some other known drug morus alba interactions.

This kind of falls into what the attending physician put on the death certificate -examples: either
"death from" primary cause
or
"death with" secondary (came after) the separate primary
 
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