Sure it is, because the SET will only be diagonal in one particular coordinate chart--the standard Schwarzschild chart, with the center of the gravitating body at the origin. More precisely, the SET will only be diagonal in the family of coordinate charts including all possible choices of "zero points" for the angular coordinates. In other words, the spherical symmetry of the spacetime ensures that, *if* we choose a chart centered on the gravitating body (i.e., the gravitating body's center of mass is at the spatial origin), we can rotate the angular coordinates however we like and the SET will still be diagonal. Spherical symmetry only requires that the tangential stress be the same in all tangential directions; it does not require that the tangential stress be the same as the radial stress.
But if the tangential stress is *not* the same as the radial stress, then if we transform to any chart whose spatial origin is *not* at the center of mass of the gravitating body, there will be off-diagonal terms in the spatial part of the SET, indicating shear stress. One obvious way to construct such a chart is to spatially rotate the standard Schwarzschild chart about any point *other* than the origin, i.e., a "spatial rotation", as DaleSpam said (with the proviso that the axis of rotation can't pass through the CoM of the gravitating body). So perhaps a better way to say what DaleSpam was saying is that "shear stress" and "anisotropic pressure" are just two different ways of describing the same physics, using two different coordinate charts.
Note that changing charts does not change the fact that the *spacetime* is spherically symmetric. Spherical symmetry just means there are a set of 3 spacelike Killing vector fields with the appropriate commutation relations. It doesn't require the stress to be isotropic.