Differentiating large and small bodies in physics involves understanding the influence of gravity and surface tension, which can vary significantly based on scale. The Bond number is a relevant concept for comparing these scales, as it helps determine the dominance of gravitational versus surface tension forces. However, defining "large" and "small" is not straightforward and often depends on context, as there are no strict size thresholds. Classical physics typically applies to most scales, but quantum mechanics and relativity come into play at atomic scales and near-light speeds, respectively. Ultimately, the classification of bodies as large or small is subjective and reliant on the specific reference frame used.