I'd avoid anything distracting, like the colors and fancy headers. Some bold and italics would be okay to highlight things that are especially relevant to the job you're applying for, but anything more than that becomes distracting and is more likely to get it tossed into the circular file as unprofessional.
Sadly, it seems that the only thing needed to make a CV or resume stand out nowadays is to submit it without spelling and grammatical errors! Attention to detail is a job skill many people lack.
Also, if you're sending it to a large company, many of them use scanners to read the text and put it into a database to distribute electronically in a common format. If you use unusual fonts or colors, the software may have trouble reading it, resulting in it just being rejected.
The organization is most important. Make sure the experience/skills you have that are most relevant to the job you're applying for are right at the beginning where they stand out. For students who don't usually have a lot of relevant experience yet, starting off with a section titled "Relevant Experience and Coursework" is a good format. List experience first, coursework second. Bullet each separate work experience with a brief description of skills used or responsibilities. List all the coursework under a single bullet. Then a separate section can be entitled "Other experience" to highlight any other jobs you've held that may not pertain to the job, but show you have other skills. Again, highlight skills you've needed/acquired in those jobs, and keep it relevant (for example, if you worked as a cashier, don't list "operating cash register" as a skill, but you can list "developed customer service/customer relations skills"). Once you have relevant experience post-graduation, you'll drop off a bunch of the less relevant jobs held while paying your way through school, but when just starting out, those do help to show initiative and how well you manage your time by the number of things you've accomplished well.
If you have any awards, list those too. Determining to put them at the beginning or end depends on what they are and what the job is. For example, if you won an award for chemistry and are applying for a position as a chemist, put your awards up near the top, if you won a community service award, put it nearer the bottom (it's still relevant, could show you're a team player, etc, but not as directly pertinent as any work experience).
That's really where personal style comes in, deciding what you want to highlight, what items to put at the top, what to bullet, how to emphasize your personal skill set.
I'm sure others have suggestions as well, as there are many ways to organize a CV or resume that reflect a lot of personal preferences. The most important thing is to remember someone is reading a LOT of these, and the easier it is on their eyesight, the more likely it is they'll read yours completely.
. I've blanked out the personal details for obvious reasons ;)
