CD4 and CD5 are both glycoproteins found on the surface of T cells, playing crucial roles in the immune response. CD4 is primarily known for its function as a co-receptor that assists T cells in recognizing antigens presented by MHC class II molecules, which is vital for the activation of helper T cells. In contrast, CD5 is involved in modulating T cell receptor signaling and is important for maintaining T cell tolerance and preventing autoimmunity. While both proteins are important for T cell function, their roles and mechanisms of action differ significantly. For further detailed information, various articles and references are available on platforms like Wikipedia, which can provide a comprehensive understanding of their functions in immunology.