DNA Origami: Research & Study Resources for Trapping & Folding Processes

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Discussion Overview

The discussion centers on finding research papers and study resources related to DNA origami, specifically focusing on trapping and folding processes. Participants seek to share and gather relevant academic references and insights into these processes.

Discussion Character

  • Exploratory
  • Technical explanation
  • Homework-related

Main Points Raised

  • One participant requests links to research papers and study content about trapping and folding processes in DNA origami.
  • Another participant expresses frustration at not receiving the expected help and reiterates their request for assistance.
  • A third participant suggests starting with a Wikipedia page on DNA origami, indicating that it contains several references that may be useful.
  • A participant offers a list of references from their own research on DNA topology, noting that while they may not be directly applicable, some references could describe folding processes and construction methods.
  • The provided references include various studies on DNA topology, bending, and self-assembly, with specific papers cited for their relevance to the topic.

Areas of Agreement / Disagreement

There is no consensus on specific resources or methods to address the original request, and multiple viewpoints on the applicability of shared references remain. The discussion is ongoing and unresolved.

Contextual Notes

Participants have not clarified the specific aspects of trapping and folding processes they are interested in, nor have they established the relevance of the suggested references to the original inquiry.

sudu.ghonge
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I'm working on a project in the field of DNA origami and need links to research papers and study content for the trapping processes and folding processes. Can anyone help?
 
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... Not the sort of help i expected. Incase this post was ignored because other fresh posts coming, this is just to bring it up again. Please, I need help.
 
I wrote a paper on DNA topology for genetics a couple years ago, so I can offer some references. Not sure how applicable they are to what you're looking for, but it's something. 5 and 9 should describe the folding processes and how they construct them.

1. Mirkin, SM. DNA Topology: Fundamentals. Encyclopedia of Life Sciences. 2001
2. Hardin, AH, et al. Direct measurement of DNA Bending by Type IIA Topoisomerases: Implications For Non-equilibrium Topology Simplification. Nucleic Acids Research. (2011) first published online March 17, 2011 doi:10.1093/nar/gkr109
3. Mikelsen, MB, et al. Pressure-Driven DNA in Nanogroove Arrays: Complex Dynamics Leads to Length- and Topology-Dependent Separation. Nano Letters. (2011) first published online March 1, 2011 doi:10.1021/nl1044764
4. Dorman, CJ and Corcoran, CP. Bacterial DNA Topology and Infectious Disease. Nucleic Acids Research. (2008) first published online December 10, 2008. doi:10.1093/nar/dkn996
5. Dongran, H, et al. Folding and Cutting DNA Into Reconfigurable Topological Nanostructures. Nature Nanotechnology. (2010) first published online October 3, 2010. doi:10.1038/nnano.2010.193
6. Szambowska, A, et al. Coupling and Transcription and Replication Machineries in λ DNA Replication Initiation: Evidence for Direct Interaction of E. coli RNA polymerase and the λO protein. Nucleic Acids Research. (2010) first published online September 9, 2010. doi:10.1093/nar/gkq752
7. Laponogov, I, et al. Structural Basis of Gate-DNA Breakage and Resealing by Type II Topisomerases. PLoS ONE 5(6): e11338. doi:10.1371/journal.pone.0011338
8. Yurke, B, et al. A DNA-fuelled Molecular Machine Made of DNA. Nature 406, 605-608 (10 August 2000) doi:10.1038/35020524
9. Andersen, ES, et al. Self-assembly of a Nanoscale DNA Box With a Controllable Lid. Nature 459, 73-76 (7 May 2009) doi:10.1038/nature07971
10. Ding, B, et al. Gold Nanoparticle Self-Similar Chain Structure Organized by DNA Origami. Journal of the American Chemical Society, 2010, 132 (10), pp 3248-3249 first published online February 17, 2010 doi: 10.1021/ja9101198
 
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