The discussion centers around the misconception that sleep deprivation can lead to weight loss. Participants share anecdotes, including one individual who stayed awake for 100 hours and faced serious health issues, highlighting the dangers of extreme sleep deprivation. Another contributor mentions a roommate who lost weight primarily by sleeping more and eating less, suggesting that weight loss can occur when caloric intake is significantly reduced, rather than due to lack of sleep itself. The conversation emphasizes that while the body may burn some calories while awake, the overall health risks of sleep deprivation outweigh any potential weight loss benefits. Additionally, it is noted that sleeping burns slightly fewer calories than watching TV, and engaging in sedentary activities during wakefulness does not promote weight loss. The thread concludes with a humorous take on the absurdity of weight loss trends, advocating for real physical activity over sedentary behaviors.