To find the volume inside the two spheres defined by the equations x^2+y^2+z^2=4 and (x+2)^2+(y-1)^2+(z+2)^2=4, the intersection volume can be calculated using integration. The volume of intersection is determined to be 11π/12. To set up the integral, the bounds must be established by equating the two equations, leading to the expressions for z1 and z2. The volume is then computed using the double integral V = ∬_D (z1 - z2) dA, where D represents the region of integration. This approach effectively captures the volume common to both spheres.