... how does one precisely define the size of a spatial dimension? Secondly, how does one measure it?
If you are a beginner then the first place to look is at wiki?
http://en.wikipedia.org/wiki/Degrees_of_freedom_(physics_and_chemistry )
A degree of freedom is an independent physical parameter, often called a dimension, in the formal description of the state of a physical system. The set of all dimensions of a system is known as a phase space.
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http://en.wikipedia.org/wiki/Dimension
In mathematics and physics, the dimension of a space or object is informally defined as the minimum number of coordinates needed to specify each point within it.
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http://en.wikipedia.org/wiki/Fourth_dimension
Comparatively, 4-dimensional space has an extra coordinate axis, orthogonal to the other three, which is usually labeled w.
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What I did not find in wiki was the physics implication of a fourth or more spatial dimensions. It involves expanding the definition of a closed system to preserve “conservation of energy”. To explain gravity and why it is so weak in 3d, the 4th dimension is considered to be a large sheet/brane that is parallel to our 3d and that the gravity force extends/connects into our 3d by following an exp. curve.
Using more than 3d is a way of hiding a particle/energy from our observation.
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http://en.wikipedia.org/wiki/Subatomic_particle
In particle physics, the conceptual idea of a particle is one of several concepts inherited from classical physics. This describes the world we experience, used ( for example ) to describe how matter and energy behave at the molecular scales of quantum mechanics.
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Now, for your question.
... how does one precisely define the size of a spatial dimension? Secondly, how does one measure it?
Do an exercise ... use minimum length on dimensions to achieve/realize/permit the degrees of freedom for a particle. You will find that if you assign one unit for the size of a particle then the result will be that the minimum size of the dimension will be 2 units. Any size less than one would not be permitted since that is the definition. If the dimension is equal to the size of the particle then it cannot have any degrees of freedom/movement.
A proton is 1f or 10^-15m.
The experiments being done at CERN will give us a better range on the sizes of particles.
jal