To integrate e^(-pi^2*x^2) from -infinity to infinity, the general formula for Gaussian integrals is applied: ∫ e^(-αx^2) dx from -infinity to infinity equals √(π/α) for α > 0. By substituting α with π^2, the integral evaluates to √(π/π^2), simplifying to 1/√π. The discussion also touches on the specific case where the limits of integration are equal, leading to a value of zero, but this is noted as a separate consideration. Overall, the integration of e^(-pi^2*x^2) yields a clear result based on established mathematical principles.