Just submitted my PhD dissertation

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Discussion Overview

The thread centers around a participant who has just submitted their PhD dissertation and is preparing for their defense. The discussion includes reflections on graduate student experiences, the specifics of the dissertation topic, and informal exchanges of congratulations and advice.

Discussion Character

  • Meta-discussion
  • Conceptual clarification

Main Points Raised

  • One participant mentions they are defending soon and transitioning to a full-time job in Intelligence after graduation.
  • Several participants express good wishes and congratulations regarding the dissertation submission and upcoming defense.
  • Concerns are raised by some participants about the expectations of work after graduation, with one expressing feelings of being exploited during their graduate studies.
  • Another participant inquires about the specifics of the dissertation topic, which involves an ion-conductance model of persistence dynamics in biological neurons.
  • The original poster explains that their model focuses on dominant current channels and calcium-dependent channels, while omitting certain behaviors like the refractory period.
  • There is a humorous exchange about reviewing the dissertation and potential objections to it, indicating a collegial atmosphere among participants.

Areas of Agreement / Disagreement

Participants generally express support and congratulations, but there are mixed feelings regarding the graduate experience, with some expressing feelings of exploitation. The technical aspects of the dissertation topic are discussed, but no consensus is reached on the implications of the model or the omitted behaviors.

Contextual Notes

Some participants express uncertainty about the specifics of the persistence dynamics and the implications of the model, highlighting limitations in the current discussion regarding the refractory period and its modeling.

Who May Find This Useful

Graduate students, those interested in neuroscience models, and individuals preparing for dissertation defenses may find this discussion relevant.

Pythagorean
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-Defending soon,
-Have a part-time job in Intelligence that I go full-time after officially graduating.
-Starting to see the end of the tunnel.
 
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Go back! It's a trap! They're going to expect you to work from now on!
 
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Noisy Rhysling said:
Go back! It's a trap! They're going to expect you to work from now on!

To be honest, I have felt like cheap and exploited labour through university life as a grad student.
 
Pythagorean said:
To be honest, I have felt like cheap and exploited labour through university life as a grad student.
I knew how to Google, so my lead prof. exploited that.
 
Pythagorean said:
-Defending soon,
-Have a part-time job in Intelligence that I go full-time after officially graduating.
-Starting to see the end of the tunnel.
Congratulations on completing the dissertation and getting it submitted. Best wishes for a successful defense.
 
Good luck Pyth!
 
Congratulations! (Hope the hangover isn't too bad)
 
  • #10
Good luck!
 
  • #11
Greg Bernhardt said:
So what's your thesis?

I made an ion-conductance model of persistence dynamics in a known biological neuron and extended it to the biological network. Persistence dynamics are found across species and typically involve a "switch" (a particular kind of stimulus on the neuron) to switch it from typical threshold-type neuron dynamics to persistent spiking for some duration. It's involved in some cognitive functions (the persistence acts like a sort of information memory) and basically anywhere you have rhythmically contracting muscle (like birth, egg laying, breast-feeding let down, etc).
 
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  • #12
What time frame is the persistence ? seconds ? Hours ?
 
  • #13
jim hardy said:
What time frame is the persistence ? seconds ? Hours ?

The biological neuron goes on for about half hour in a persistent state, then enters a refractory period where it can still respond as a typical threshold-type neuron but can't enter persistence mode for nearly a day. My model doesn't include any of this behavior as I put focus on developing the dominant current channels and their 2nd messengers, as well as the calcium-dependent channels responsible for persistence. So my model goes into persistence indefinitely. The refractory period requires some more elaborate 2nd-messenger modeling, I decided to go to the network and focus on onset and spread in the network and leave refractory period to the next lucky grad student.
 
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  • #14
Congratulations and good luck!
 
  • #15
Congratulations! If you made it this far, you'll almost certainly survive the oral defense unless you have a total meltdown.

Ibix said:
(Hope the hangover isn't too bad)
When I emerged from my dissertation defense, some of my fellow graduate students were waiting to haul me off to a campus watering-hole. :biggrin:
 
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  • #16
Thanks for the congrats, everyone!

I think my defense will go fine. I'll probably get grilled a bit, but that's the nature of the beast.
 
  • #17
Pythagorean said:
My model doesn't include any of this behavior as I put focus on developing the dominant current channels and their 2nd messengers, as well as the calcium-dependent channels responsible for persistence. So my model goes into persistence indefinitely. The refractory period requires some more elaborate 2nd-messenger modeling

Can you send me a pre-print so I can pick it apart and send my objections to the qualifying committee? :oldsmile:

I'll send you a copy of the rebuttal first, before I send it to the committee, promise :oldtongue:
 

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