- #1
Aymeric
- 12
- 0
Hello,
Many diseases are characterized by the presence of lactic acidosis, with lowered blood pH supposedly due to lactate (as in diabetes for example).
My question is: how is it possible, since lactate coming out of the lactate dehydrogenase from pyruvate is... lactate, not lactic acid. So how does lactic acidosis occur when lactate is already ionized (thus unable to further dissociate and release a proton) when produced?
Thanks.
Many diseases are characterized by the presence of lactic acidosis, with lowered blood pH supposedly due to lactate (as in diabetes for example).
My question is: how is it possible, since lactate coming out of the lactate dehydrogenase from pyruvate is... lactate, not lactic acid. So how does lactic acidosis occur when lactate is already ionized (thus unable to further dissociate and release a proton) when produced?
Thanks.