Learning MATLAB for solving ODEs related to macromolecular drug flow is generally considered manageable, especially for those familiar with C syntax, as the language has a gentle learning curve. Tutorials are available online to help beginners get started. MATLAB combines elements of C, Fortran, and shell scripting, making it easier for those with experience in any two of these languages. However, for complete novices to programming, the learning process may be challenging, though not insurmountable. While MATLAB itself is user-friendly, the broader concepts of programming can present difficulties. Overall, with dedication and the right resources, newcomers can successfully learn MATLAB for their research projects.