MCQ-Localization of recessive alleles on Polytene chromosome

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SUMMARY

The discussion centers on the localization of recessive alleles on Polytene chromosomes, specifically addressing the correct answer to a multiple-choice question, which is option (c). Polytene chromosomes arise from the duplication of diploid nuclei without chromatid separation, resulting in multiple DNA strands per chromosome. The conversation highlights the importance of understanding the implications of wild-type (WT) alleles being recessive and the inheritance of deletions across chromatids. Participants emphasize the need to verify the correctness of the provided answer and suggest a logical approach to deducing allele positions based on experimental results.

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  • Understanding of Polytene chromosomes and their formation
  • Knowledge of wild-type (WT) alleles and their recessive nature
  • Familiarity with genetic complementation and allele mapping
  • Basic logic puzzle-solving skills
NEXT STEPS
  • Research the mechanisms of Polytene chromosome formation and their significance in genetics
  • Study genetic complementation tests and their applications in allele identification
  • Learn about the implications of recessive alleles in genetic inheritance
  • Explore methods for visualizing and interpreting genetic data from experiments
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Genetics students, researchers in molecular biology, and educators seeking to understand the complexities of allele localization and Polytene chromosome analysis.

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Correct option-(c)

Polytene chromosomes develop from the chromosomes of diploid nuclei by successive duplication of each chromatid without their separation, as such, each chromosome has several strands of DNA.
Here they are talking about the WT alleles being recessive. ALso if the initial unduplicated normal chromosome has the deletion, it will be passed down to all the chromatids.

I'm not getting the table.
 
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TytoAlba95 said:
Homework Statement:: N.A
Relevant Equations:: N.A

Correct option-(c)

Polytene chromosomes develop from the chromosomes of diploid nuclei by successive duplication of each chromatid without their separation, as such, each chromosome has several strands of DNA.
Here they are talking about the WT alleles being recessive. ALso if the initial unduplicated normal chromosome has the deletion, it will be passed down to all the chromatids.

I'm not getting the table.

I will give you that the question layout is possibly somewhat unhelpful in using the numbers 1234 to mean different things, and also the letters abcd, They could've used Greek letters and Roman numbers helpfully .

You should know that by the ethos and rules of Homework Help here, help does not kick in if you just say 'I'm not getting it'.

However as this question has been here for some time unanswered, so I guess it was not evident to any of us (I cannot remember having had to deal with a similar problem) I'll point out that you should at least be able to get the question in the sense that you should be able to verify that the given answer, c, works, and the others don't. Actually that is all you are asked to do. It would however be a preparation for the more difficult problem if you were asked, given only the experimental results what is the order.

For this I take it you know what the paragraph preceding the table means. To deduce the order I suggest you look at the cases where the wild-type fails to be produced by complementation in only one of the deletions. Can you say anything about the position of the allele in such cases?
 
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I'm also late. I agree that the question is confusing in its designations. I didn't understand until I figured out that the bands (Del 1, etc.) represent which alleles will be wild-type. From there it is just a logic puzzle where you connect each allele position (1, 2, etc.) to the allele itself (a, b, etc.). From Del 2 and Del 3, for example, you can solve for position 4, so what would that be?
 
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