In advanced HTGR designs, the integrity of the coated particle fuel in its function as primary FP barrier depends strongly on the maximum fuel temperatures reached during irradiation and in accidents. These fuel temperatures are predicted by reactor system calculations using a combination of codes and models for core neutronics, decay heat power, and system T/Hs. So-called melt-wire experiments performed in Germany’s Arbeitsgemeinschaft Versuchsreaktor reactor (AVR) showed the unexpected presence of in-core hot spots, where maximum local operating temperatures were much higher than predicted with codes like those now being used by the PBMR developers. Moreover, the AVR’s true maximum local operating temperatures remain unknown due to measurement inadequacies in those experiments. For all advanced HTGR designs, significant uncertainties also exist in predicting the maximum fuel temperatures and vessel temperatures during heatup accidents. Such uncertainties relate to basic data like irradiation- and temperature-dependent thermal conductivities, as well as the integral effects of variable local power densities with conductive, radiative, and convective heat transfer through the core and surrounding structures. Appropriate data measurements and system analysistools will therefore be needed to support the staff’s understanding and assessment of factors that govern fuel temperatures and uncertainties in relation to fuel integrity and HTGR safety margins.