To parameterize a circle of radius r centered at (a, b, c) in a plane defined by the equation x + y + z = 6, one approach is to start with a circle in the xy-plane and apply a rotation to align it with the desired plane. After rotation, the circle can be translated to the center point (a, b, c). An alternative method involves finding two unit vectors that are perpendicular to the normal vector of the plane and to each other. The parameterization can then be expressed as R(t) = ⟨a, b, c⟩ + r * u * cos(t) + r * v * sin(t). This method effectively describes the circle's position and orientation in three-dimensional space.