?? What do you mean by "re-write it as a DE in terms of the first derivative"? You should wind up with TWO first order differential equations.
If, for example, you have the second order equation, Y"(x)= f(x, Y, Y'), you could let U(x)= Y' so that your equation becomes U'= f(x, Y, U). Because that equation still involves Y, you need two equations: U'= f(x,Y,U) and Y'= U. Now run two simultaneous first order de solvers.
For example, if you are given Y"= f(x,Y,Y') with initial conditions Y(x0)= Y0, Y'(x0)= Y1, that is equivalent to the system of equations U'= f(x,Y,U) , Y'= U with conditions Y(x0)= Y0, U(x0)= Y1. Run, say, Runge-Kutta fourth order for both Y and U using the values calcuated for both Y and U at each step.