Taking Physics C without prior calculus knowledge may put a student at a disadvantage, as the course is calculus-based. While it is possible to manage with algebraic techniques, understanding calculus concepts can significantly enhance problem-solving abilities, especially for more complex topics. If Physics C is the first physics course, calculus is helpful but not strictly necessary. However, for students who have already taken two physics classes by their junior year, calculus becomes increasingly important. To bridge the gap in knowledge, utilizing resources like Khan Academy or the book "No Bullshit Guide to Math and Physics" by Ivan Savov can provide essential calculus understanding and its application in physics.