The three PDCoV sequences identified in the Haitian children were the result of at least two separate zoonotic transmissions from related non-recombinant porcine strains that probably occurred within a similar time frame.
Independent infections of porcine deltacoronavirus among Haitian childrenhttps://www.nature.com/articles/s41586-021-04111-z
Could PDCoV merge or otherwise interact with SARS-Cov-2 in the same population, potentially through co-infection?In each case, the emergence of Coronavirus in our species has been associated with zoonotic transmissions from animal reservoirs underscoring how prone such pathogens are to spill over and adapt to new species. Among the four recognized genera of the family Coronaviridae, human infections reported so far have been limited to alphacoronaviruses and betacoronaviruses. Here we identify porcine deltacoronavirus strains in plasma samples of three Haitian children with acute undifferentiated febrile illness.
In the conclusion section, a rather significant comment "To our knowledge, this is the first report of PDCoV infection in humans, consistent with viraemia and systemic dissemination. The recent divergence of human strains detected in Haiti from their closest pig strains detected in China and the USA in the phylogeny highlights how little we know about the spreading of PDCoV and its introduction in Haiti."