We have that $$f(x) = \frac{q^n x^n (\pi - x)^n}{n!}$$ and also $$I_n = \sum_{j=0}^n (-1)^j \left(f^{(2j)}(\pi) + f^{(2j)}(0)\right)$$I believe all the derivatives evaluated at ##\pi## or ##0## for which ##j < n## will be zero (since they will still contain a multiplicative ##x## or ##(\pi - x)## term).
So the sum will I think reduce to a constant term ##(-1)^n \left(f^{(2n)}(\pi) + f^{(2n)}(0)\right)##. But after doing ##2n## derivatives, the ##n!## on the denominator should be canceled since we will have multiplied by all of ##n##, ##(n-1)##, etc.
I don't know if this is right, and it's certainly not a "proof" of any sort, it's just how I pictured it.