Assuming that the uncertainlty principle is a fact of the world, as many physicists firmly believe, how does this affect our deep undersranding of knowledge? In the Middle Ages the consideration of bodyless angels led to subtle considerations of what we can know and how we can know it. Monistic science has traditionally had only a naive approach to epistomaology. But I think that quantum constraints, like the angels of old, should return nuance to the field. What do you think?