Charging capacitors in the 300-450 volt range can be done by connecting them to a suitable DC power supply, ideally with a series resistor to control the charging rate. It's crucial to ensure safety when working with high voltages, as charged capacitors can retain lethal charges for extended periods. Capacitors can be charged individually and then connected in series for higher voltage applications, but this should be done cautiously, ideally using a switch. The use of bleeder resistors is recommended to safely discharge capacitors when power is removed. Seeking professional help, such as consulting an electrician, can be a wise decision for complex projects involving high voltages.