Toxicology Resources: Wikipedia, Principles of Biochemical Toxicology & More

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The discussion focuses on various resources and templates related to toxins, toxicology, and poisoning, highlighting their importance in understanding chemical interactions and toxicity. Key resources include Wikipedia templates on toxins and toxicology, as well as databases like the Comparative Toxicogenomics Database (CTD) and the Pharmacogenomics Knowledge Base (PharmGKB). The conversation emphasizes the significance of predicting toxicity based on chemical structure, which is an active area of research, supported by references to recent studies and guides on hazardous properties of chemical substances. Case studies on specific toxins, such as ochratoxin and tetrodotoxin, are mentioned, underscoring their relevance in neurophysiology and toxicology research. The discussion also touches on the QSAR model for classifying chemical toxicity and the importance of understanding the relationship between chemical properties and their toxic effects.
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http://en.wikipedia.org/wiki/Template:Toxins => Wikipedia template on toxins

http://en.wikipedia.org/wiki/Template:Toxicology => Wikipedia toxicology template

http://en.wikipedia.org/wiki/Template:Poisoning_and_toxicity

http://books.google.com/books?id=jW...&dq=toxicology&ei=2aiFTf-BOYKglATgv_yjAQ&cd=1 => Principles of Biochemical Toxicology

http://ctd.mdibl.org/query.go?type=ixn =>Chemical–Gene Interaction Query - CTD

http://www.pharmgkb.org/ => The Pharmacogenomics Knowledge Base [PharmGKB]

http://potency.berkeley.edu/ => The Carcinogenic Potency Project (CPDB)

http://www.reactome.org/ReactomeGWT/entrypoint.html#FrontPage.3625

http://ctd.mdibl.org/ => The Comparative Toxicogenomics Database - CTD

http://en.wikipedia.org/wiki/Toxicogenomics

Nice Physics Forums replies to toxicologically significant properties:

mg/kg - how relevant?: https://www.physicsforums.com/showthread.php?t=462694

protein folding/computational toxicology: https://www.physicsforums.com/showthread.php?t=466253

Predicting toxicity based on chemical structure (this is a VERY hot field for research right now):

http://potency.berkeley.edu/pdfs/structure_tox_on_web.pdf

http://books.google.com/books?id=-C...LilASt08XNBw&cd=4#v=onepage&q=organic&f=false => A comprehensive guide to the hazardous properties of chemical substances

http://www.citeulike.org/user/InquilineKea/article/8980563 => Toward molecular design for hazard reduction—fundamental relationships between chemical properties and toxicity - this is a really recent (and readable) paper that shows a way to classify a chemical's potential toxicity based on its chemical structure. Summary at http://www.sciencenews.org/view/feature/id/70925/title/Better_by_Design

http://en.wikipedia.org/wiki/QSAR => QSAR model

http://www.jstor.org/stable/3433032 => very early system of classifying chemicals toxic to rodents

Case studies of particular toxins:

http://en.wikipedia.org/wiki/Ochratoxin
http://en.wikipedia.org/wiki/Tetrodotoxin => very important for neurophysiology research

More specific resources:
(I have many resources about amphetamine toxicity in particular, but I won't list them here for now)

http://www.longecity.org/forum/topic/47231-amphetamine-neurotoxicity-reductionprevention/ => very interesting discussion about research papers on amphetamine toxicity in particular (just be leery about the posts that advocate a particular consumption pathway).
 
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