Ultrasound and Chemical Repair of DNA: Is There Scientific Evidence?

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The discussion centers on the scientific evidence regarding the effects of ultrasound on DNA repair, particularly in the context of chemotherapy-resistant ovarian cancer cells. A referenced article suggests that exposure to ultrasound may reduce the resistance of these cancer cells by affecting DNA repair mechanisms. However, there are concerns about the validity of the findings, particularly regarding the mechanics of ultrasound, which operates at millimeter wavelengths, raising questions about how it could cause targeted subcellular damage. Additionally, the lack of information on the energy levels used in the study is noted, with speculation that they may be lower than those associated with UV damage. The conversation highlights a need for further exploration and clarification of the mechanisms involved in ultrasound's impact on cellular processes.
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Is there any SCIENTIFIC evidence of the effect of ultrasound on chemical repair of DNA? As in, is there peer-reviewed research in this?

Thanks.
 
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This atricle shows that a chemotherapy-resistant ovarian cancer cell line ( because of DNA repair) becomes less resistant on exposure to ultrasound.

http://www.ingentaconnect.com/content/jws/uog/2009/00000033/00000003/art00017
 
I couldn't read the whole article, just the abstract, but it doesn't make any sense. Ultrasound (MHz) has wavelengths in the millimeter range- how can targeted subcellular damage occur?

The abstract also did not mention the incident energy level, but I suspect it's much lower than occurs with UV damage.
 
Thanks for the link Jim. I can't access the full article, but if you can, could you address Andy's question? I'm curious.
Thanks :)
 
Andy Resnick said:
I couldn't read the whole article, just the abstract, but it doesn't make any sense. Ultrasound (MHz) has wavelengths in the millimeter range- how can targeted subcellular damage occur?

The abstract also did not mention the incident energy level, but I suspect it's much lower than occurs with UV damage.
According to the introduction the ultrasound treatment leads to increased intracellular drug levels, I haven't read the study so I can't comment on the validity.
 
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