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higherme
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Hi
I don't know what novel genes are. Any help?
Thanks
I don't know what novel genes are. Any help?
Thanks
higherme said:because I'm trying to find orthologs on this gene called san-1 from C. elegans, But it doesn't seem to have any. So my assignment saids to try finding it with its novel gene.
So novel gene is not really a gene? I'm confused. does it have a name though?
qraal said:Isn't a gene that doesn't belong to a previous identified gene family, thus it has no comparable genes in other species?
Novel genes are genes that have been predicted by Ensembl on the basis of similarity to protein or cDNA sequences. They cannot be mapped with confidence to existing entries in any public sequence database.
Monique said:It gave domains when you did a blast, did you try blasting the protein sequence to other species? That's how you find orthologs. The fact that it has a Mad3 domain is a big clue as to the function and possible orholog of the protein.
Besides doing the interspecies blast search you can also search the literature on Pubmed and the C. elegans worm database at Wormbase.
Novel genes are newly discovered genes that have not been previously identified or characterized. These genes may have unique functions, sequences, or expression patterns that distinguish them from other known genes.
Novel genes are identified through various techniques, such as genome sequencing, gene expression analysis, and computational analysis. These methods involve comparing DNA sequences and gene expression patterns to known genes to identify any differences or new sequences.
Novel genes can play a variety of roles in biological processes, such as regulating gene expression, encoding proteins with new functions, and contributing to disease development. They may also play a role in evolutionary processes, as they can introduce new traits and adaptations to a species.
Yes, novel genes can be inherited from parent organisms. They can also arise through mutations and genetic rearrangements within an individual's own genome. However, not all novel genes are passed down to the next generation and may be lost through natural selection.
Novel genes can be studied in the laboratory through techniques such as gene cloning, gene expression analysis, and functional studies. These methods allow scientists to manipulate and analyze the structure and function of novel genes to better understand their roles in biological processes.