What are some resources for modeling fluid flow in porous mediums?

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Discussion Overview

The discussion revolves around resources and methodologies for modeling fluid flow in porous mediums, specifically in the context of improving the bone marrow biopsy procedure to reduce pain. It encompasses theoretical aspects and practical applications related to fluid dynamics in biological contexts.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • One participant expresses a need for resources on modeling fluid flow in porous mediums, particularly for the context of bone marrow biopsies.
  • Another participant suggests starting with Darcy's law as a foundational concept for understanding fluid flow in porous media.
  • A different participant questions the consistency of the biopsy location and proposes the idea of a permanent access port to alleviate repeated procedures.
  • Additional resources are shared, including links to Wikipedia articles on Darcy's law and groundwater flow equations, as well as specific texts and journal articles that may provide relevant information.
  • One participant mentions a position at the University of Leeds focused on developing computational tools for modeling fluid flow in porous bone structures, indicating ongoing research in this area.
  • There is a personal note of empathy for those undergoing bone marrow biopsies, highlighting the discomfort associated with the procedure and the potential for targeted delivery of treatments.

Areas of Agreement / Disagreement

Participants do not reach a consensus on the best resources or methods for modeling fluid flow in porous mediums, and multiple viewpoints regarding the biopsy procedure and potential improvements are presented.

Contextual Notes

The discussion includes various assumptions about the applicability of suggested resources and the effectiveness of proposed methods, which remain unverified within the thread.

pmb_phy
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I'm trying to create a model of the procedure of having a bone marrow biopsy done in order to seek ways of eliminating the pain which one has to endure during this process. I'll need to start with modeling fluid flow in a porous medium but this is something I've never done before and have never seen done. Does anyone know of a decent text which I can pick up which touches base on this specific topic of fluid flow in a porous medium?

Pete
 
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pmb_phy said:
I'm trying to create a model of the procedure of having a bone marrow biopsy done in order to seek ways of eliminating the pain which one has to endure during this process. I'll need to start with modeling fluid flow in a porous medium but this is something I've never done before and have never seen done. Does anyone know of a decent text which I can pick up which touches base on this specific topic of fluid flow in a porous medium?
Pete
For starters, check up on Darcy's law.
 
Sorry to hear that you're still having to go through that, pmb. Is the biopsy always done in the same area? The reason that I ask is because I'm wondering why they can't install a permanent access port, such as a cobalt or SS spigot, in the bone to save having to bore holes every time.
 
Adding to arildno's comment - http://en.wikipedia.org/wiki/Darcy's_Law

http://en.wikipedia.org/wiki/Groundwater_flow_equation

http://www.fys.uio.no/~eaker/thesis/node4.html

Some background - http://www.jgmaas.com/scores/facts.html

Most detailed discussions are found in journal articles or textbooks which one must purchase.

Here is a text - http://www.midlandit.co.uk/particletechnology/ - but I do not know if it is what you want. Excerpt from Chapter 3 - http://www.midlandit.co.uk/particletechnology/fluidflow.pdf

Here is an article which may be of interest - http://epubs.siam.org/sam-bin/dbq/article/39276 (must be purchased, or locate it in a university library)

Interestingly - the University of Leeds, School of Mechanical Engineering has a position for a Fellow who will develop a series of computational tools for modelling the flow of injectable cements into porous bone structures. http://wwwnotes2.leeds.ac.uk/jobs/unijob.nsf/0/e9825f52248c3bcc8025709a003a8d62?OpenDocument

If your the one having a bone marrow biopsy, sorry to hear that. My brother went through that and chemotherapy - and it was most unpleasant. I think there is need to deliver chemotherapeutical compounds directly to the point of interest rather than poisoning the whole body.
 
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