Angular acceleration is considered positive when an object rotating clockwise slows down because the acceleration is directed counterclockwise, opposing the motion. The discussion clarifies that in a right-handed coordinate system, counterclockwise is positive and clockwise is negative. When an object accelerates in the opposite direction of its motion, it indicates deceleration. The participants emphasize the importance of understanding the direction of angular speed and acceleration in relation to the defined coordinate system. Ultimately, the key takeaway is that the sign of angular acceleration depends on its direction relative to the object's motion.