The number zero is essential in mathematics and science as it serves as the additive identity, allowing for the definition of equality and enabling operations like differentiation and integration in calculus. Without zero, mathematical systems would struggle with concepts like limits and would lack a coherent way to express differences, making calculations cumbersome, as seen in systems like Roman numerals. The discussion highlights that while alternative systems could theoretically exist, they would face significant limitations and complexities. Zero also plays a crucial role in defining various mathematical structures, such as groups and fields, which are foundational to modern mathematics. Overall, the absence of zero would lead to a breakdown in many mathematical and scientific principles.