Hydrogen bonds and binding energy question

In summary, the conversation is about comparing different methods of solvation in a computational lab. The question is raised about the significance of positive and negative binding energy, with conflicting answers from different sources. The conversation then shifts to evaluating acetic acid and water hydrogen bonding and calculating binding energy. The expert asks if the sources are using the same definition of binding energy.
  • #1
ReidMerrill
66
2
I'm doing a computational lab about binding energy and comparing different methods of solvation. What does positive and negative binding energy signify? Half of the places I look say the more positive the binding energy the stronger the interaction between the molecules. Other places say the more negative the binding energy the stronger the interaction. Which is correct?
We're evaluation acetic acid and water hydrogen bonding. To get the binding energy were taking the energy of acetic acid + energy of water - energy of acetic acid and hydrogen bonded water
 
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  • #2
Are you sure the sources use the same definition of binding energy?

The more energy you need to break or change a bond the stronger it is.
 

1. What is a hydrogen bond?

A hydrogen bond is a type of intermolecular force that occurs between a hydrogen atom bonded to a highly electronegative atom (such as oxygen or nitrogen) and another electronegative atom in a different molecule. This bond is weaker than covalent or ionic bonds, but still important for the structure and function of many biological molecules.

2. How do hydrogen bonds contribute to the stability of molecules?

Hydrogen bonds contribute to the stability of molecules by holding them together through attractive forces between the positively charged hydrogen atom and the negatively charged atom it is bonded to. These bonds can also create a network of interactions between molecules, further increasing their stability.

3. What is the significance of hydrogen bonds in biological systems?

Hydrogen bonds play a critical role in maintaining the structure and function of biological molecules such as proteins, DNA, and RNA. They help stabilize the three-dimensional shape of these molecules, allowing them to perform their specific functions in the body.

4. How is the strength of a hydrogen bond determined?

The strength of a hydrogen bond is determined by the difference in electronegativity between the two atoms involved in the bond, as well as the distance between them. The greater the electronegativity difference and the closer the atoms, the stronger the bond will be.

5. How does binding energy relate to hydrogen bonds?

Binding energy is the energy required to break a bond between two molecules. In the case of hydrogen bonds, this energy is relatively low, making them easy to break and allowing for flexibility in biological systems. However, the cumulative effect of many hydrogen bonds can contribute to a significant amount of binding energy, which is important for the stability of larger biomolecules.

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