Study molecular conformation using optical spectroscopy?

In summary, the conversation discusses the use of optical spectroscopy to study the molecular conformation of conjugated polyelectrolyte (CPE). While previous studies have been done on CPE in aqueous solution, the individual wants to know if this method can also be used on dried CPE. They mention the need for additional experiments, such as X-ray diffraction or Raman spectroscopy, to fully understand the changes in structure that may occur when the CPE is dried.
  • #1
Yinxiao Li
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I want to study the molecular conformation of conjugated polyelectrolyte (CPE) using optical spectroscopy. Obviously a lot of people have used optical spectroscopy to study the structure of conjugated polymers, including this conjugated polyelectrolyte. However, they did in when the CPE is in aqueous solution. My question is that can I study its structure after it is dried using the same method?

The basic method is to compare the results of (e.g. emission spectra) to decide if the structure has been changed.

 
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  • #2
However, the results of dried CPE may be different from that in aqueous solution due to the aggregation of the polyelectrolyte chains and other possible conformational changes. Therefore, additional experiments such as X-ray diffraction or Raman spectroscopy may be required for a more detailed structural understanding of the CPE after it is dried.
 

1) What is optical spectroscopy?

Optical spectroscopy is a scientific technique used to study the interaction of light with matter. It involves using light of different wavelengths to analyze the structure, composition, and properties of molecules and materials.

2) How does optical spectroscopy help in studying molecular conformation?

Optical spectroscopy can provide information about the energy levels and transitions of molecules, which can be used to determine their spatial arrangement and conformation. By analyzing the absorption, emission, or scattering of light, researchers can obtain valuable insights into the structure and dynamics of molecules.

3) What types of optical spectroscopy are commonly used in studying molecular conformation?

Some commonly used types of optical spectroscopy for studying molecular conformation include UV-Vis spectroscopy, fluorescence spectroscopy, Raman spectroscopy, and circular dichroism spectroscopy. Each of these techniques offers different advantages and can provide unique information about molecular structure and conformation.

4) What are the benefits of using optical spectroscopy for studying molecular conformation?

Optical spectroscopy is a non-invasive and non-destructive technique, meaning that it does not require any physical contact with the sample and does not alter its properties. This makes it ideal for studying delicate molecules and biological systems. Additionally, optical spectroscopy is a relatively fast and sensitive method, allowing for the analysis of a large number of samples in a short amount of time.

5) What are some applications of studying molecular conformation using optical spectroscopy?

The study of molecular conformation using optical spectroscopy has numerous applications in various fields, including chemistry, biology, materials science, and pharmaceuticals. This technique can be used to analyze the structure and function of biomolecules, determine the purity and composition of materials, and even aid in drug discovery and development.

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