The secretory pole in secretory cells

In summary, the Golgi apparatus is a system of membranes that appears as fibrils under the electron microscope. The apical fibrils are located between the secretory pole and the nucleus in secretory cells. The secretory pole refers to the end of a cell that is exposed to the outside surface, where most of the secretion occurs. It can also refer to polarized structures within the cell, such as the Golgi apparatus.
  • #1
Asmaa Mohammad
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Hello,

I read that Golgi Apparatus when examined below the electronic microscope, appears a network of fibrils either apical or perinuclear.

And it is apical when the Golgi apparatus is between the secretory pole and the nucleus in secretory cells.

I don't know what exactly is the "secretory pole"? So an explanation in a simple language will be great.

Thanks :)
 
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  • #2
I would call the Golgi apparatus a system of membranes rather than fibrils.
Fibrils to me implies they are fiber-like such as microtubules, intermediate fibers or micro-filiments (actin fibers)
The Golgi complex is a series of membranes and the spaces they enclose and separate from the cytoplasm. That's what it looks like in EM (electron microscope).

The secretory pole is the end of a cell in an epithelium (a sheet of cells) that is exposed to the outside surface (which topologically includes the lumen of things like the intestine, which is an invaginated outside surface).
Epithelial cells are polarized having apical and basal (or basolateral) surfaces. The apical surface is where most of the secretion of vesicular contents occurs in epithelial cells. It can therefore be called the secretory pole of the cell.
Within cells other things may also be also polarized, such as the golgi apparatus and centrioles.
 
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1. What is the secretory pole in secretory cells?

The secretory pole in secretory cells refers to the specific region of the cell where secretory products are released. It is characterized by an abundance of organelles involved in protein synthesis and secretion, such as the endoplasmic reticulum and Golgi apparatus.

2. How does the secretory pole differ from other regions of the cell?

The secretory pole is distinct from other regions of the cell due to its specialized function in secreting products. It contains a higher concentration of organelles involved in secretion and has a unique morphology compared to other areas of the cell.

3. What types of cells have a secretory pole?

Many different types of cells can have a secretory pole, including glandular cells, epithelial cells, and specialized cells in organs such as the pancreas and salivary glands. These cells have a high demand for secretion and therefore require a specialized region for this function.

4. What is the role of the secretory pole in cellular function?

The secretory pole plays a crucial role in cellular function by facilitating the production and release of secretory products. This can include hormones, enzymes, mucus, and other substances that are necessary for proper bodily function and homeostasis.

5. How is the secretory pole related to diseases and disorders?

The secretory pole can be affected by various diseases and disorders, as disruptions in the secretion process can lead to imbalances in the body. For example, in cystic fibrosis, a genetic disorder, the secretory pole in epithelial cells is unable to properly secrete mucus, causing respiratory and digestive issues. Additionally, tumors can develop in glandular cells, disrupting the function of the secretory pole and leading to conditions such as cancer.

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