According to Susan Blackmore, vision researcher Dr. Tomasz S. Troscianko of the University of Bristol speculated:
If you started with very little neural noise and it gradually increased, the effect would be of a light at the centre getting larger and larger and hence closer and closer...the tunnel would appear to move as the noise levels increased and the central light got larger and larger...If the whole cortex became so noisy that all the cells were firing fast, the whole area would appear light. (Blackmore 1993: 85)
Blackmore attributes the feelings of extreme peacefulness of the NDE to the release of endorphins in response to the extreme stress of the situation. The buzzing or ringing sound is attributed to cerebral anoxia and consequent effects upon the connections between brain cells (op. cit., 64).
Blackmore, Susan J. Dying to Live: Near-death Experiences, (Buffalo, N.Y. : Prometheus Books, 1993).
Dr. Karl Jansen has reproduced NDEs with ketamine, a short-acting hallucinogenic, dissociative anaesthetic.
The anaesthesia is the result of the patient being so 'dissociated' and 'removed from their body' that it is possible to carry out surgical procedures. This is wholly different from the 'unconsciousness' produced by conventional anesthetics, although ketamine is also an excellent analgesic (pain killer) by a different route (i.e. not due to dissociation). Ketamine is related to phencyclidine (PCP). Both drugs are arylcyclohexylamines - they are not opioids and are not related to LSD. In contrast to PCP, ketamine is relatively safe, is much shorter acting, is an uncontrolled drug in most countries, and remains in use as an anaesthetic for children in industrialised countries and all ages in the third world as it is cheap and easy to use. Anaesthetists prevent patients from having NDE's ('emergence phenomena') by the co-administration of sedatives which produce 'true' unconsciousness rather than dissociation.*
According to Dr. Jansen, ketamine can reproduce all the main features of the NDE, including travel through a dark tunnel into the light, the feeling that one is dead, communing with God, hallucinations, out-of-body experiences, strange noises, etc. This does not prove that the NDE is nothing but a set of physical responses, nor does it prove that there is no life after death. It does, however, prove that an NDE is not compelling evidence for belief in either the existence of a separate consciousness or of an afterlife.