A negative change in current, represented by di/dt<0, indicates that the current is increasing in the opposite direction, which can be confusing when considering the flow of positive charges. The discussion highlights the importance of understanding both the direction of current and the slope of the current-time graph, as both can be positive or negative. In alternating current (AC), the current oscillates, leading to periods where both the current and its rate of change can be negative. This duality means that a negative dq/dt can signify either a decrease in charge over time or charges moving in the opposite direction. Overall, the interpretation of negative current changes requires careful consideration of the context and the definitions used.