Surface plasmon resonance (SPR) chips are noted for their high cost, leading to inquiries about the nanofabrication techniques used in their production. While SPR can be observed on any metal surface without chips, specific applications necessitate coated chips, typically with gold or silver, due to their low losses and high chemical stability. The discussion highlights that metal nanoparticles can be produced using simple techniques, but the exact methods for creating SPR chips remain unclear. Suggestions include metal ion implantation on glass surfaces and various chemical routes as potential fabrication techniques. The focus is on the application of SPR in measuring reaction rate constants, emphasizing the importance of the chip's chemical environment for accurate detection.
