Molecular Weight for nucleotides

AI Thread Summary
The discussion clarifies the meaning of "daltons" and "g/M" in the context of molecular weight. A dalton is defined as an atomic mass unit, with one mole of a substance corresponding to its molecular weight in grams. Specifically, for carbon-12 (C12), its mass is exactly 12 Da, meaning one mole weighs 12 grams. The term "g/M" is confirmed to stand for grams per mole (g/mol), not grams per mole per liter (g/mol/L). The conversation also touches on the calculation of molecular weight for nucleotides, emphasizing that the molecular weight reflects the mass of one mole of the molecule. The reference to carbon as a standard is noted due to its ease of purification, which justifies its use as a whole number in molecular weight calculations.
mountain
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When it says; "Molecular Weight: daltons (g/M)" What does daltons mean and what does (g/M) stand for? Does g/M stand for g/mol or what?

How can they calculate Molecular Weight for nucleotides?


Thanks for any inputs.
 
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A dalton is an atomic mass. For instance C12 has a mass of 12.0000 Da. The mw is the mass of 1 mole of a particular molecule. By definition 1 mole of carbon atoms weighs 12 grams.
 
Thanks.

But what does M stand for in g/M?
 
mountain said:
Thanks.

But what does M stand for in g/M?

You had it right...mole.
 
Monique said:
A dalton is an atomic mass. For instance C12 has a mass of 12.0000 Da. The mw is the mass of 1 mole of a particular molecule. By definition 1 mole of carbon atoms weighs 12 grams.
(why only four zeros?)

(1) C12 has a mass of 12 Da (by definition; exactly 12, there is no uncertainty)
(2) a mol of C12 atoms weighs 12 grams (by definition)

From (1) and (2) it follows that a dalton is the number of grams that go into a mol (gram/mol)
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(1) C12 = 12 Da <--> mol C12 = mol 12 Da
(2) mol C12 = 12 gram
(substitute 2 into 1) 12 gram = mol 12 Da <--> gram/mol = Da
 
doesn't g/M mean g/mol/L?
 
its not exactly 12, and its not exactly 16 for oxygen either

but they decided to make it 12 anywho. so just use 12 as a whole number

6 protons = 6 x 1.007277 6.043662
6 neutrons = 6 x 1.008665 6.051990
6 electrons = 6 x 0.000548 0.003288
Total 12.098940
 
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Carbon was easy to purify, that is why they used it as a reference and why it is the whole number 12.
 
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