Maybe a fifth spatial dimension isn't the appropriate way to describe how universes are separated in hilbert space, I'll take your word for it. Is there any conception of a "distance" that would make sense?
The influences becomes extremely small extremely quick, assigning a "distance" would not give anything interesting I think.
In MWI, you always have observers which observe "probable" (in the sense of probabilistic interpretations (now: PIs)) events with a large amplitude and observers which observe "improbable" events with a small amplitude.
While this is not a theoretic problem, this gives no direct way to explore the amplitude distributions - we could not do interesting science with that. However, there is a flaw in this argument.
Let's look at PIs again: We could be unlucky and do not get an interference pattern in double slits at all. The probability is just incredibly low.
In the same way, you can perform science with MWI with correct result in all worlds with correspond to large probabilities in PIs.To make this a bit more formal:
Assume that the whole universe can be described as the evolution of a wave function. Develop some theory about the world which can describe the evolution of the wave function. Note that, given appropriate initial conditions, the wave function can split into a number of different parts, which are (in really good approximation) independent of each other. Each part is called a world.
Define a
measure for worlds, which is just the integral over the amplitude squared over their region in phase space.
The evolution has to conserve the measure for all worlds (PI equivalent: probabilities always add up to 1). The theory now allows to predict how the wave function can split into several parts by things usually called "observation".
Define a test as a series of measurements in some way. Sort the possible results in two groups: One with a large measure (and preferably, but not necessarily, a small set of different measurement results) and one with all other results with a small sum of amplitude squares. Publish that you will perform this test (that is good scientific practice!) and that the test is a success in all worlds which are part of the group with large measure. Perform the test.
Now, some worlds will see a success and some will not. But here is the trick: If the theory was right, most of the measure will see a success. If not (in a significant way), a large part of the measure will see a failure.
With more and more tests, every theory which is wrong gets discarded in worlds containing a measure of ~1*. A correct theory will see a lot of confirmations and kept in worlds containing a measure of ~1*. A lot of worlds will come to wrong scientific conclusions, but their total measure goes to 0.
Comparison to PIs: There are many ways how experiments can go wrong, but the probability of all experiments going wrong tends to 0.*strictly speaking, human scientists do not exist in all worlds, but this does not matter. It can be scaled to the fraction of the world with humans inside.