If you have studied matrices at all then you should know this basic property: the equation Ax= y has a unique solution if and only if A is invertible: [itex]x= A^{-1}y[/itex]. And that is only true if A has non-zero determinant.
The equation Ax= 0 always has the "trivial" solution, x= 0. It has other solutions if and only if its determinant is 0.