Can a Hormone Really Determine Our Weight and Aging Process?

  • Thread starter Thread starter Ishop
  • Start date Start date
  • Tags Tags
    Scientific
AI Thread Summary
Dr. Papaconstantino in Galveston, TX, is conducting research on obesity and aging using lab mice. His obesity study involves two identical mice, one injected with leptin, a hormone linked to weight regulation. The findings suggest that food intake may not be the primary factor in obesity, as the leptin-deficient mouse is significantly overweight compared to its leptin-injected counterpart. Additionally, Dr. Papaconstantino has mice that are living over double the normal lifespan, raising interest in potential aging interventions. He is also credited with developing face lotions that improve skin appearance. While there is limited information available online regarding his weight research, a link to his work on aging was shared in the discussion. Participants expressed curiosity about the specifics of the mice's food intake and the methods used to extend their lifespan.
Ishop
Just thought this was some interesting information.

A Doctor Papaconstantino in Galveston TX is currently working on two things. One, what makes people fat and thin, Two, how to slow down or stop aging. The research has not gone beyond research mice yet, but he has two lab mice for the weight issues. Each from birth has been feed percise amounts of food at the same times of day. The ffod is actually wieghed and there is no way for excess food to get to them. Both mice are identical except that one has been injected with "lepton". A harmone that most living things (including humans) have. It has been noticed that large people usaully have very little of this harmone and thin people have a lot. The mouse that has very little "lepton" is very fat. The other is very thin. Apparently food intake isn't as prodominent in the cause of obesidy as we think.

The aging mice are interesting as well. I don't have as much inside information as I do about the "lepton" mice, but apparently somehow he has three mice that are all living past DOUBLE the normal lifespan of a mouse. In otherwords the oldest in human years would be about 220 years old!

Also, you know those face lotions that make your skin smooth and wrinkle free? You can thank Dr Papconstantino for that...his invention :)

Comment if you wish, just thought it would be interesting.
 
Biology news on Phys.org
There does exist another forum for general science. This is the philosophy forum, not the dietary one, but I think I'll go find something to eat now...
 
true, and if someone wants to move the thread to there that's fine...im too lazy to do it. Besides, I spend most my time here and thought it was just interesting info.
 
Very interesting, Ishop. Would you happen to have a link, to a site that discusses his work?
 
This one shows some stuff about aging.

http://www.hbcg.utmb.edu/faculty/papaconstantinou/

Cant find anything on the weight issue though. All my information is first hand knowledge from one of the workers involved.
 
Last edited by a moderator:
OK, about the mice: how much of the food did they actually eat? Could it be that the thin mice didn't touch the food of the 'lepton hormone' (never heard of it). The aging thingie is not new thought.. I'd have to read what exactly they did in the mice to achieve this..
 
Deadly cattle screwworm parasite found in US patient. What to know. https://www.usatoday.com/story/news/health/2025/08/25/new-world-screwworm-human-case/85813010007/ Exclusive: U.S. confirms nation's first travel-associated human screwworm case connected to Central American outbreak https://www.reuters.com/business/environment/us-confirms-nations-first-travel-associated-human-screwworm-case-connected-2025-08-25/...
Chagas disease, long considered only a threat abroad, is established in California and the Southern U.S. According to articles in the Los Angeles Times, "Chagas disease, long considered only a threat abroad, is established in California and the Southern U.S.", and "Kissing bugs bring deadly disease to California". LA Times requires a subscription. Related article -...
I am reading Nicholas Wade's book A Troublesome Inheritance. Please let's not make this thread a critique about the merits or demerits of the book. This thread is my attempt to understanding the evidence that Natural Selection in the human genome was recent and regional. On Page 103 of A Troublesome Inheritance, Wade writes the following: "The regional nature of selection was first made evident in a genomewide scan undertaken by Jonathan Pritchard, a population geneticist at the...
Back
Top