Humans still have a reasonable chance of beating computers in certain games, particularly those that involve complex strategies and intuitive understanding, such as Arimaa and Charades. The discussion highlights that when competing against computers, players are often actually competing against algorithms designed by humans. With advancements in machine learning, particularly deep learning, computers are increasingly capable of outperforming humans in various games, including poker and Go. DeepMind's AlphaGo has demonstrated this by defeating top human players in Go, showcasing the potential of AI to learn and adapt independently. The conversation also touches on the unpredictability of machine learning outcomes, as even the creators may not fully understand the decision-making processes of these systems. Concerns are raised about the implications of AI advancements, especially with the integration of quantum computing.