Direct sunlight does not appear to reactivate urushiol-induced rashes from prior exposure, but T cells can retain immune memory, potentially leading to heightened reactions upon re-exposure. Urushiol, found in poison ivy, oak, and sumac, triggers an autoimmune response by altering skin proteins, which may cause rashes to recur if there is unrecognized contact with the allergen. The longevity of immune memory can vary, lasting from years to a lifetime, depending on the individual and allergen. Immediate washing with water is recommended after suspected exposure, though there is no consensus on the best method to remove urushiol. OTC treatments like Zanfel may provide relief, but their effectiveness can vary among individuals.