Canine family tree reflects human hand

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Most genetic variation in modern dogs has been introduced by humans through selective breeding, according to researchers who compared dog and wolf DNA to construct a canine family tree. An analysis of DNA samples from 414 purebred dogs across 85 breeds revealed that breeds can be categorized into four main groups: ancient hounds resembling wolves, large Mastiffs, working dogs like collies, and sporting dogs such as hounds and terriers. This study highlights the significant impact of human intervention in dog evolution and the genetic diversity present within the canine genome.
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WASHINGTON - Most genetic variation in modern dogs was introduced by humans through selective breeding programs, researchers have found.

This is among the surprising findings of a comparison of dog and wolf DNA by researchers building a canine family tree.

Researchers took DNA samples from 414 purebred dogs representing 85 breeds to see how the canine genome accounts for the smallest Pekinese, curly poodle or herding border collie.

Scientists used a computer program and statistical analysis to identify a dog's breed based on the subtle differences in its genetic profile.

Geneticist Elaine Ostrander of the Fred Hutchinson Cancer Research Centre in Seattle and her colleagues found the breeds evolved into four main groups:

* An ancient group of older hounds like the Afghan, dogs of Asian origin, such as the Chinese Shar-pei, and the northern Spitz dogs like the Siberian Huskey most closely resembled the wolf.
* The Mastifs such as Rottweilers, bulldogs and boxers that share large bodies and square-shaped heads.
* Working dogs like collies and sheep dogs.
* Sporting dogs like hounds and terriers.

http://www.cbc.ca/stories/2004/05/20/sci-tech/dogs_dna040520


For the Science Article
http://www.sciencemag.org/cgi/content/abstract/304/5674/1160
 
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