Cell biology/biochemistry quandary

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Phosphate buffered saline (PBS) can effectively suspend erythrocytes for short periods. The discussion centers on the potential interaction of ionic compounds, specifically cesium fluoride (CsF), with PBS. It is noted that the cell membrane is generally impermeable to most ions, meaning Cs+ and F- ions are unlikely to enter erythrocytes unless specific ion channels are present. The key question raised is whether Cs+ and F- would form new compounds with phosphate or other components in the solution or if they would remain dissociated as free ions. The consensus suggests that without specific conditions for interaction, these ions are expected to stay in solution as free ions rather than forming new compounds.
diewlasing
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If you have a phosphate buffered saline, you can suspend erythrocytes in it for a few minutes. But, for the sake of argument, can one as ionic compounds to the the PBS, like CsF, will it combine to form new compounds and cross the cell membrane. Or will it dissociate and stay in solution as ions? Obviously biology/biochemistry is not my forte.

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The cell membrane is impermeable to most ions. As long as Cs+ and F- cannot enter the erythrocyte through some ion channel, they should not enter the cell.
 
right, but will they form compounds with the phosphate or others in solution or will they remain free ions?
 

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