Countercurrent and concurrent exchanger?

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Countercurrent and concurrent exchangers differ primarily in how they maintain concentration gradients. In countercurrent exchange, blood and water flow in opposite directions, allowing for a continuous gradient that enhances efficiency, especially in the kidneys. This mechanism is crucial for urine concentration, as it preserves the high osmolarity of the medulla while supplying blood. The countercurrent multiplier actively transports salt from the loop of Henle into the vasa recta, amplifying the osmotic gradient. Understanding these principles is essential for grasping renal physiology and the mechanisms behind urine concentration.
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Hello everyone,

I searched the net but I don't understand the difference.

BLO0D FLOW ---------------------------------->
0% .......… saturation
0% .......… saturation
WATER FLOW <-------------------------------

Countercurrent

BLO0D FLOW ---------------------------------->
0% .......… saturation
100%........… saturation
WATER FLOW --------------------------------->

Concurrent

I understand how equilibrium would be reached in concurrent but I don't understand how counter current maintains a concentration gradient. Please explain in simple language. Also if you can explain the above diagrams, I got it from net I don't understand them much. Thanks :smile:
 
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Those diagrams don't make too much sense...maybe the concurrent (simple exchange), but the countercurrent should look like:

BLOOD ----------------->
0%---------------> 90%
10%-------------> 100%
WATER <-----------------

It's clear from the above that along the length of the tubes, there is flow from the higher to the lower.

Now, in the kidney, the tubes form a loop, with high osmolarity in the medulla:

->600 mOsm-------->1200 mOsm----------->600 mOsm--->

And this allows for the supply of blood to the medulla without altering the high osmolarity of the medulla (which would abolish the urine concentrating mechanism).

The mechanism of the countercurrent multiplier refers to the active transport of salt out of the loop of Henle into the vasa recta. This amplifies the small gradient between the limbs to create a large gradient along the length of the limb of the loop.
 
Andy Resnick said:
Those diagrams don't make too much sense...maybe the concurrent (simple exchange), but the countercurrent should look like:

BLOOD ----------------->
0%---------------> 90%
10%-------------> 100%
WATER <-----------------

It's clear from the above that along the length of the tubes, there is flow from the higher to the lower.

Now, in the kidney, the tubes form a loop, with high osmolarity in the medulla:

->600 mOsm-------->1200 mOsm----------->600 mOsm--->

And this allows for the supply of blood to the medulla without altering the high osmolarity of the medulla (which would abolish the urine concentrating mechanism).

The mechanism of the countercurrent multiplier refers to the active transport of salt out of the loop of Henle into the vasa recta. This amplifies the small gradient between the limbs to create a large gradient along the length of the limb of the loop.

Thanks a lot for the response Andy :smile: Your answer is just what I need but I'm finding it difficult to understand.

0%---------------> 90%
10%-------------> 100%

Could you please tell me how to get those values and what is this the percentage of? Please excuse my poor understanding in this area.
 
The numbers are placeholders; the material I referred to draws an analogy with thermal transport. Silbernagl and Despopoulos "Color Atlas of Physiology" (Thieme) is as close to an ideal reference as I have seen.
 
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